<div dir="ltr"><div class="gmail_default" style="font-family:georgia,serif"><br></div><div class="gmail_default" style="font-family:georgia,serif"><br></div><div class="gmail_default" style="font-family:georgia,serif">Details at <a href="http://iwbbio.ugr.es/sessions_proposals.php" style="font-family:arial">http://iwbbio.ugr.es/sessions_proposals.php</a></div>
<table class="" style="margin:0px 0px 2em 10px;padding:0px;border-style:solid;border-width:1px 0px 5px;width:460px;table-layout:auto;border-collapse:collapse;empty-cells:show;border-bottom-color:rgb(153,153,153);border-top-color:rgb(48,74,92);background-color:rgb(48,74,92);color:rgb(64,64,64);font-family:Verdana,sans;font-size:11.111111640930176px;background-repeat:no-repeat no-repeat">
<tbody style="margin:0px;padding:0px;border-style:solid;border-width:0px;background-repeat:no-repeat no-repeat"><tr class="" style="margin:0px;padding:0px;border-style:solid;border-width:0px;background-repeat:no-repeat no-repeat">
<th style="margin:0px;padding:4px 1em;border-style:solid;border-width:0px;min-height:30px;font-weight:normal;color:rgb(255,255,255);background-repeat:no-repeat no-repeat"><strong style="margin:0px;padding:0px;border-style:solid;border-width:0px;background-repeat:no-repeat no-repeat">SS17</strong></th>
<td style="padding:4px 1em;border-style:solid;border-width:1px 0px;background-color:rgb(237,237,237);border-bottom-color:rgb(153,153,153);border-top-color:rgb(153,153,153);background-repeat:no-repeat no-repeat"><strong style="margin:0px;padding:0px;border-style:solid;border-width:0px;background-repeat:no-repeat no-repeat"><font color="4d84bc" style="margin:0px;padding:0px;border-style:solid;border-width:0px;background-repeat:no-repeat no-repeat">Annotation and Curation of Uncharacterized Proteins: Systems Biology Approaches</font></strong> <br style="margin:0px;padding:0px;border-style:solid;border-width:0px;background-repeat:no-repeat no-repeat">
<br style="margin:0px;padding:0px;border-style:solid;border-width:0px;background-repeat:no-repeat no-repeat">A hypothetical protein (HPs) is a protein whose existence is predicted but whether or not it is expressed remains uncertain. However, many HPs in the recent past have been known to be expressed in vivo. With various methods known to identify components in cell membrane, the functional significance of thousands of proteins especially those that do not have function, not expressed, unique or common among genomes is least understood. Apart from this, many HPs might turn out to be pseudogenes at a later point of time and the use of these proteins remain mis-conducive. To circumvent the problem, several methods to easily screen functional candidates among many hypothetical proteins, use of feature selection algorithms and testing the efficacy of these proteins in terms of precision and accuracy using stochases have widely been covered. With experimental procedures for HP function prediction being low throughput by nature, there has been a need to precisely know their functions for a better understanding of the underlying biological mechanism. We would invite authors interested in these niche areas of annotating uncharacterized proteins and functional genomics for their contribution in any of the following areas, not just limited to the following but to a broader purview:<ul style="margin:6px 0px 1.2em;padding:0px;border-style:solid;border-width:0px;list-style-type:none;list-style-position:outside;background-repeat:no-repeat no-repeat">
<li style="margin:0px 0px 6px;padding:0px 0px 0px 10px;border-style:solid;border-width:0px;background-image:url(http://iwbbio.ugr.es/img/interior/lista-nivel1.png);text-align:justify;background-repeat:no-repeat no-repeat">
Computational flow for the functional annotation of uncharacterized proteins using motif discovery, sequence and structural similarity, structural homology, hypothome (interactome of hypothetical proteins) or combination of data from highly similar non-interacting proteins (Similactors).</li>
<li style="margin:0px 0px 6px;padding:0px 0px 0px 10px;border-style:solid;border-width:0px;background-image:url(http://iwbbio.ugr.es/img/interior/lista-nivel1.png);text-align:justify;background-repeat:no-repeat no-repeat">
Predictive approaches based on Gene Ontology (GO).</li><li style="margin:0px 0px 6px;padding:0px 0px 0px 10px;border-style:solid;border-width:0px;background-image:url(http://iwbbio.ugr.es/img/interior/lista-nivel1.png);text-align:justify;background-repeat:no-repeat no-repeat">
Feature selection and machine learning methods.</li><li style="margin:0px 0px 6px;padding:0px 0px 0px 10px;border-style:solid;border-width:0px;background-image:url(http://iwbbio.ugr.es/img/interior/lista-nivel1.png);text-align:justify;background-repeat:no-repeat no-repeat">
Diseasome approaches.</li></ul><strong style="margin:0px;padding:0px;border-style:solid;border-width:0px;background-repeat:no-repeat no-repeat">Organizers: <br style="margin:0px;padding:0px;border-style:solid;border-width:0px;background-repeat:no-repeat no-repeat">
<a href="mailto:alfredo.benso@polito.it" style="margin:0px;padding:0px;border-style:solid;border-width:0px;outline:none;color:rgb(77,132,188);text-decoration:none;background-repeat:no-repeat no-repeat">Prof. Alfredo Benso</a></strong>, Department of Control and Computer Engineering, Politecnico di Torino (Italy)<br style="margin:0px;padding:0px;border-style:solid;border-width:0px;background-repeat:no-repeat no-repeat">
<strong style="margin:0px;padding:0px;border-style:solid;border-width:0px;background-repeat:no-repeat no-repeat"><br style="margin:0px;padding:0px;border-style:solid;border-width:0px;background-repeat:no-repeat no-repeat">
<a href="mailto:prash@bioclues.org" style="margin:0px;padding:0px;border-style:solid;border-width:0px;outline:none;color:rgb(77,132,188);text-decoration:none;background-repeat:no-repeat no-repeat">Dr. Prashanth Suravajhala</a></strong>, Founder of Bioclues.org and Director of Bioinformatics.org </td>
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</font><span lang="EN-US"><font><div dir="ltr"><span lang="EN-US"><font color="#000099" face="times new roman,serif"><span>Prashanth Suravajhala, PhD.</span></font></span></div><div><font face="times new roman,serif">Homepage: </font><a href="http://www.bioinformatics.org/wiki/Prash" target="_blank"><font face="times new roman,serif">http://www.bioinformatics.org/wiki/Prash </font></a><font face="times new roman,serif"> </font><br>
</div><p style="margin:0px 0px 0pt"><font face="times new roman,serif">Linkedin: <span lang="EN-US"><font><a href="http://dk.linkedin.com/in/prashbio" target="_blank"><font color="#0000ff">http://dk.linkedin.com/in/prashbio</font></a> </font></span></font></p>
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</font><p style="margin:0cm 0cm 0pt;line-height:normal"><span lang="EN-US" style="line-height:115%"><font></font></span> <font face="georgia, serif"><span lang="EN-US" style="line-height:115%"><font face="times new roman,serif">"<span>Scientific  research is one of the most exciting and rewarding of occupations." ~Frederick Sanger</span></font></span><span style="line-height:115%">  </span></font></p>


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