<html><head><meta http-equiv="Content-Type" content="text/html charset=windows-1252"></head><body style="word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space;">Dear colleagues,<div><br></div><div>We are looking to recruit a <b>Computational Biologist in Brain Research</b> - see the post below for details. </div><div><br></div><div><div><div>If you know a strong candidate who would like to work on computational genomics of human neurodegenerative diseases in Harvard Medical School, I would be appreciated if you could pass this message to him/her.</div><div><br></div></div><div>Many thanks for your help,</div><div><br></div></div><div>Xianjun Dong</div><div>---------------------------------------------------<br>Instructor, Department of Neurology<br>Harvard Medical School<br>Faculty of Neurology Department<br>Brigham and Women's Hospital<br><br>Tel: (+1)617-768-8691<br>Address: 65 Landsdowne St, </div><div>Cambridge, MA 02139<br>Blog: <a href="http://onetipperday.blogspot.com">http://onetipperday.blogspot.com</a></div><div><br></div><div>==================================================================================</div><div><br></div><div><div>Harvard Medical School and Brigham & Women’s Hospital </div><div>Postdoctoral Position Available in The Neurogenomics Laboratory </div><div> </div><div><b>Computational Biologist in Brain Research </b></div><div><br></div><div>The Neurogenomics Laboratory envisions and is building a future precision medicine for Parkinson’s, </div><div>Huntington’s, and other neurologic diseases, where genome-wide DNA, RNA, and various regulatory </div><div>information is integrated for much earlier diagnosis, personalized prognosis, tailored treatments, and response </div><div>tracking. We are looking for an enthusiastic, highly motivated, science-driven and experienced postdoctoral </div><div>fellow to join our team to unravel how the genome functions in the human brain. The focus of this project is to </div><div>answer two key questions for the future of neuroscience: How do GWAS-derived genetic risk variants cause </div><div>brain disease? How can we harness this information for precision therapies? Genotyping, RNA-seq, </div><div>microRNA-seq, and allele-specific gene expression analyses in >>100 human brains and biofluid samples will </div><div>be performed to address this questions. See <a href="http://www.scherzerlaboratory.org/">http://www.scherzerlaboratory.org/</a> for more background. </div><div> </div><div><b>Your tasks</b>: By joining the bioinformatics team and working together with molecular biologists from the wet lab, </div><div>the Postdoctoral Fellow will perform a variety of standard analysis, such as RNA-seq, small RNA-seq, </div><div>expression Quantitative Trait Locus (eQTL), allele-specific gene expression, and advanced integrative analysis </div><div>such as network and pathway analyses. </div><div> </div><div>Other responsibilities include: </div><div>• Develop and implement algorithms and statistical methods to analyze large-scale sequencing data </div><div>• Design and develop innovative data visualization methods to support genome analysis </div><div>• Publish and present novel research findings in academic journals and conferences </div><div>• Develop and maintain collaborations both within Harvard Medical School and also with outside researchers </div><div>in academia and industry. </div><div> </div><div><b>Your qualifications</b>: Applicants are expected to have Ph. D. or equivalent doctoral degree in bioinformatics, </div><div>computer science, genomics, physics, or statistics. Ideal applicant should have strong programming skills in (R </div><div>& (Perl | Python | C | C++ | Java)) and good knowledge in algorithms and tools development. Experience in Unix </div><div>shell scripting is a big plus. Prior experience in analyzing high-throughput sequencing data (RNA-seq, ChIP-seq, </div><div>small RNA sequencing etc.) is preferred. Advanced usage of large biological repositories, such as UCSC </div><div>Genome Browser, Ensembl is a plus. Knowledge in gene regulation is a plus. Experience in GWAS, eQTL, </div><div>allele-specific gene expression is a plus. Excellent English communication skills are required. Prior experience </div><div>in genetics or neurosciences is encouraged. Candidates must have a track record in publication. Furthermore, the </div><div>ability to work in a team and experience in the supervision of students are an asset. </div><div> </div><div>This fully funded position is available for an initial one-year appointment with the possibility of extension. </div><div>Salary will be commensurate with experience. </div><div> </div><div>Please submit your application, including a statement of research interests, a biosketch, and three </div><div>references to Kris Vernon at <a href="mailto:kvernon@partners.org">kvernon@partners.org</a> and cc Dr. Scherzer <a href="mailto:cscherzer@partners.org">cscherzer@partners.org</a>.</div></div></body></html>