<div dir="ltr"><div class="gmail_default" style="font-family:verdana,sans-serif;color:#444444"><br></div><br><div class="gmail_quote">---------- Forwarded message ----------<br>From: <b class="gmail_sendername">Bernd Bodenmiller</b> <span dir="ltr"><<a href="mailto:bernd.bodenmiller@imls.uzh.ch">bernd.bodenmiller@imls.uzh.ch</a>></span><br>

Date: Sun, Feb 23, 2014 at 7:45 PM<br>Subject: Postdoc position in systems biology of immune cell plasticity available<br>To: <a href="mailto:linding@cbs.dtu.dk">linding@cbs.dtu.dk</a><br><br><div lang="DE-CH" link="blue" vlink="purple">

<p class="MsoNormal"><span lang="EN-US"><u></u> <u></u></span></p><p class="MsoNormal"><span lang="EN-US">We currently have an ongoing project in which we started to reprogram tumor-supporting immune cells into tumor-fighting immune cells. We are now searching for a postdoctoral fellow in quantitative biology to generate network models of the reprogramming process based on CyTOF experiments/data. Ideally, the same person would also have some interest in performing some simple follow experiments in the lab.<u></u><u></u></span></p>

<p class="MsoNormal"><span lang="EN-US"><u></u> <u></u></span></p><p class="MsoNormal"><span lang="EN-US">Do you by chance know anyone who might be interested? I would also be happy if you could spread the word in northern Europe </span><span lang="EN-US" style="font-family:Wingdings">J</span><span lang="EN-US"> about this position.<u></u><u></u></span></p>

<p><span lang="EN-US"><u></u> <u></u></span></p><p><span lang="EN-US">Thanks!<u></u><u></u></span></p><p><span lang="EN-US"><u></u> <u></u></span></p><p><span lang="EN-US">Cheers,<u></u><u></u></span></p><p><span lang="EN-US">Bernd </span><span lang="EN-US"><u></u><u></u></span></p>

<p class="MsoNormal"><span lang="EN-US" style="color:#1f497d"><u></u> <u></u></span></p><p class="MsoNormal"><span lang="EN-US" style>The add can be found under </span><span lang="EN-US" style="color:#1f497d"><a href="http://www.nature.com/naturejobs/science/jobs/379767-postdoc-in-systems-biology-at-university-of-zurich-in-collaboration-with-roche-zurich-switzerland" target="_blank">http://www.nature.com/naturejobs/science/jobs/379767-postdoc-in-systems-biology-at-university-of-zurich-in-collaboration-with-roche-zurich-switzerland</a> </span><span lang="EN-US" style><u></u><u></u></span></p>

<p class="MsoNormal"><span lang="EN-US" style><u></u> <u></u></span></p><p style="margin-right:0in;margin-bottom:.25in;margin-left:0in;background:white"><strong><span lang="EN-US" style="font-size:9.5pt;font-family:"Arial","sans-serif"">The position:</span></strong><span><span lang="EN-US" style="font-size:9.5pt;font-family:"Arial","sans-serif""> </span></span><span lang="EN-US" style="font-size:9.5pt;font-family:"Arial","sans-serif""><br>

A position is available for a postdoctoral fellow interested in the systems biology of tumor-associated immune cells (TAICs) and their role in the progression of cancer. The selected candidate will use mass cytometry (CyTOF) data to generate and refine signaling network models to describe<span> </span><span>TAIC</span><span> </span>plasticity. Our ultimate goal is to predict and validate network modulations that control<span> </span><span>TAIC </span>plasticity. The candidate will perform experiments<span> </span><span>AND</span><span> </span>drive the development of the systems biology network model. The postdoctoral fellow will be located at the University of Zurich and will interact with Roche research groups. This project is supported by SystemsX, the Swiss Initiative in Systems Biology for 2 years with the option to extend for a third year.<u></u><u></u></span></p>

<p style="margin-right:0in;margin-bottom:.25in;margin-left:0in;background:white;text-align:start;word-spacing:0px"><strong><span lang="EN-US" style="font-size:9.5pt;font-family:"Arial","sans-serif"">The successful candidate will:</span></strong><span lang="EN-US" style="font-size:9.5pt;font-family:"Arial","sans-serif""><br>

• Systematically modulate and reprogram TAICs to change their functional state at the bench<br>• Become proficient in mass cytometry (CyTOF), a recently developed high-capacity single-cell proteomics technology<br>• Use mass cytometry data to generate network models to predict in silico optimal modulation strategies<br>

• Experimentally validate predictions to discover potential new targets for therapeutic intervention<br>• Aim for results <span style="background:white">relevant for human health, publishable in highly visible journals</span><u></u><u></u></span></p>

<p style="margin-right:0in;margin-bottom:.25in;margin-left:0in;background:white;text-align:start;word-spacing:0px"><strong><span lang="EN-US" style="font-size:9.5pt;font-family:"Arial","sans-serif"">Apply by:</span></strong><span><span lang="EN-US" style="font-size:9.5pt;font-family:"Arial","sans-serif""> </span></span><span lang="EN-US" style="font-size:9.5pt;font-family:"Arial","sans-serif""><br>

Send a cover letter (including an explanation of your motivation), CV, and at least two references to Prof. B. Bodenmiller to<span> </span></span><span style="font-size:9.5pt;font-family:"Arial","sans-serif""><a href="mailto:bernd.bodenmiller@imls.uzh.ch" target="_blank"><span lang="EN-US" style>bernd.bodenmiller@imls.uzh.ch</span></a></span><span lang="EN-US" style="font-size:9.5pt;font-family:"Arial","sans-serif"">.<span> </span><br>

Prof. Bernd Bodenmiller, Institute of Molecular Life Sciences, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.<span> </span></span><span style="font-size:9.5pt;font-family:"Arial","sans-serif""><a href="http://www.imls.uzh.ch/research/bodenmiller.html" target="_blank"><span style>http://www.imls.uzh.ch/research/bodenmiller.html</span></a>…<u></u><u></u></span></p>

<p class="MsoNormal"><span lang="EN-US" style><u></u> <u></u></span></p></div></div><br><br clear="all"><div><br></div>-- <br><div dir="ltr"><p style="margin:0px"><span style="font-family:verdana,sans-serif">Best wishes,</span></p>

<p style="margin:0px"><span style="font-family:verdana,sans-serif"><br></span></p><p style="margin:0px"><span style="font-family:verdana,sans-serif">Prof Dr Rune Linding</span></p><p style="margin:0px"><span style="font-family:verdana,sans-serif"><br>

</span></p><p style="margin:0px"><span style="font-family:verdana,sans-serif">Slotsvej 84B - DK-2920 Charlottenlund, Denmark</span></p><p style="margin:0px"><span style="font-family:verdana,sans-serif">Mobile: +45 2365 1941 Phone: +45 3940 1941</span></p>

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