<div dir="ltr"><div class="gmail_default" style="font-family:verdana,sans-serif;color:#444444"><span style="font-family:arial;color:rgb(34,34,34)">Dear all,</span><br></div><div class="gmail_quote"><div bgcolor="#FFFFFF" text="#000000">
<br>
We have two openings in the group for a PhD student and a Post-doc.
Please circulate!<br>
<br><h1><a href="http://employment.ku.dk/faculty/?show=683948" target="_blank">Postdoc
position in cell-migration and systems-scale drug discovery in
Linding Lab</a></h1>
<div>
<p>A shared postdoc position is available between Symphogen A/S
and the laboratory of Prof Dr Rune Linding, a world-leading
network biologist whose research focuses on the mechanisms by
which cells use signaling networks to respond and adapt to
changes in their environment. We are seeking a highly motivated
and brilliant postdoc to join our highly dynamic, productive and
stimulating lab.<br>
<br>
<strong>The group and our research</strong><br>
The Linding Laboratory is a network biology research group based
at the Biotech Research and Innovation Centre at the University
of Copenhagen (BRIC). Our lab explores biological systems by
both generating high-throughput data and developing algorithms
aimed at predicting cell behavior with accuracy similar to those
of weather or aircraft models. A major focus of our lab is
studying cellular signal processing and decision-making during
cancer progression.<br>
<br>
Symphogen A/S (<a href="http://www.symphogen.com" target="_blank">www.symphogen.com</a>)
is a privately held biotech company based in Ballerup,
immediately outside the center of Copenhagen, Denmark. The
Company currently employs 90 people. Symphogen´s proprietary
technology offers a method for the production of unlimited
amounts of highly purified, antigen-specific, recombinant
antibody mixtures - a new class of therapeutic anti-bodies with
a number of prominent advantages compared to existing monoclonal
antibody or immunoglobulin therapies. This new antibody
technology has a significant market potential and the company
has developed a broad pipeline with two products in clinical
development and several preclinical programs.</p>
<p><strong>Project/The research project(s)</strong><br>
In this position, the successful applicant will perform
large-scale integrative studies, combining next generation
sequencing, global phospho-proteomics and high content
screening, with computational models in order to identify the
signaling networks involved in cell migration. Following target
identification the applicant will generate novel antibody based
anti-cancer therapies that can be taken further into
pre-clinical and clinical testing.<br>
<br>
The identified targets and therapies will be utilized in a
network medicine project focused on developing novel treatments
for cancer and will be related to our recent studies on
phosphorylation networks and network medicine (Creixell et al.
2012 Nature Biotechnology, Erler & Linding Cell 2012, Bakal,
Linding et al. Science 2008, Tan et al. Science 2009 and Tan et
al. Science 2011 and Jørgensen et al. Science 2009). The project
is a collaboration between the Linding Laboratory, Prof. Doug
Lauffenburger’s lab at MIT, Prof. Norbert Perrimon’s lab at
Harvard, Assoc. Prof. Janine Erler’s lab at BRIC, Symphogen A/S,
Silicon Graphics Inc. and PerkinElmer GmbH.<br>
</p>
<p><a href="http://employment.ku.dk/faculty/?show=683948" target="_blank">More
details and application:
http://employment.ku.dk/faculty/?show=683948</a></p>
<hr size="2" width="100%"></div>
<h1><a href="http://employment.ku.dk/phd/?show=684305" target="_blank">International
PhD Fellowship in computational systems-scale drug discovery in
Linding Lab</a></h1>
<div>
<p>A PhD position is available in the laboratory of Prof. Dr. Rune
Linding a world-leading network biologist whose research focuses
on the mechanisms by which cells use signaling networks to
respond and adapt to changes in their environment. We are
seeking a highly motivated and brilliant student to join our
highly dynamic, productive and stimulating lab.</p>
<p><strong>The group and our research</strong><br>
The Linding Laboratory is a network biology research group based
at the Biotech Research and Innovation Centre at the University
of Copenhagen (BRIC). Our lab explores biological systems by
both generating high-throughput data and developing algorithms
aimed at predicting cell behavior with accuracy similar to those
of weather or aircraft models. A major focus of our lab is
studying cellular signal processing and decision-making during
cancer progression.</p>
<p><strong>Project/ The research project(s)</strong><br>
In this position, the successful applicant will develop
computational models to integrate genomic, quantitative
phospho-proteomic and phenotypic data to identify the signaling
networks involved in cell migration. The applicant will also
work on complex image analysis problems, such as tracking the
movement of individual cells in real time.</p>
<p>The developed models will be utilized in a network medicine
project focused on identifying novel targets and therapies for
the treatment of cancer and will be related to our recent
studies on phosphorylation networks and network medicine
(Creixell et al. 2012 Nature Biotechnology, Erler & Linding
Cell 2012, Bakal, Linding et al. Science 2008, Tan et al.
Science 2009 and Tan et al. Science 2011 and Jørgensen et al.
Science 2009). The project is a collaboration between the
Linding Laboratory, Prof. Doug Lauffenburger’s lab at MIT, Prof.
Norbert Perrimon’s lab at Harvard, Assoc. Prof. Janine Erler’s
lab at BRIC, Symphogen A/S, Silicon Graphics Inc. and
PerkinElmer GmbH. The successful applicant will be based at the
Linding Laboratory but will have the opportunity to work with
and at other partner sites.</p>
<p><a href="http://employment.ku.dk/phd/?show=684305" target="_blank">More details
and application: http://employment.ku.dk/phd/?show=684305</a></p><span class="HOEnZb"><font color="#888888">
</font></span></div><span class="HOEnZb"><font color="#888888">
<br>
<pre cols="72">--
Xavier Robin, PhD
Cellular Signal Integration Group (C-SIG) - Linding Lab
Biotech Research and Innovation Center (BRIC) - University of Copenhagen
Anker Engelundsvej, DTU Campus, Building 301, DK-2800 Lyngby, DENMARK
Mobile: +45 42 799 833
<a href="http://www.lindinglab.org" target="_blank">www.lindinglab.org</a> - <a href="http://www.bric.ku.dk" target="_blank">www.bric.ku.dk</a>
</pre>
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</div><br><br clear="all"><div><br></div>-- <br><div dir="ltr"><p style="margin:0px"><span style="font-family:verdana,sans-serif">Best wishes,</span></p><p style="margin:0px"><span style="font-family:verdana,sans-serif"><br>
</span></p><p style="margin:0px"><span style="font-family:verdana,sans-serif">Prof Dr Rune Linding</span></p><p style="margin:0px"><span style="font-family:verdana,sans-serif"><br></span></p><p style="margin:0px"><span style="font-family:verdana,sans-serif">Slotsvej 84B - DK-2920 Charlottenlund, Denmark</span></p>
<p style="margin:0px"><span style="font-family:verdana,sans-serif">Mobile: +45 2365 1941 Phone: +45 3940 1941</span></p></div>
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