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<p class="MsoNormal" align="center" style="text-align:center"><span style="font-size:28pt">Postdoc Protein Bioinformatics <span></span></span></p>
<p class="MsoNormal" align="center" style="text-align:center"><span style="font-size:18pt">Arne Elofsson, Stockholm University.<span></span></span></p>
<p class="MsoNormal" align="center" style="text-align:center"><span style="font-size:16pt"><a href="http://bioinfo.se/">http://bioinfo.se/</a><span></span></span></p>
<p class="MsoNormal"><span style="font-size:16pt"><span> </span></span></p>
<p class="MsoNormal"><b><span style="font-size:16pt">Theme: </span></b><span style="font-size:16pt">We
are developing state of the art method to predict protein features, including
membrane protein topology, protein structure and protein model quality. In addition
we have a general interest in protein evolution.<span></span></span></p>
<p class="MsoNormal"><b><span style="font-size:16pt">Location: </span></b><span style="font-size:16pt">We
are located at Science for Life Laboratory, Stockholm Sweden.<span></span></span></p>
<p class="MsoNormal"><b><span style="font-size:16pt">Group: </span></b><span style="font-size:16pt">Friendly
environment with significant freedom.<span></span></span></p>
<p class="MsoNormal"><b><span style="font-size:16pt">Positions: </span></b><span style="font-size:16pt">Tax
Free postdoc scholarships for two years, medical insurance etc.<span></span></span></p>
<p class="MsoNormal"><b><span style="font-size:16pt">Contact: </span></b><span style="font-size:16pt"><a href="mailto:arne@bioinfo.se">arne@bioinfo.se</a><span></span></span></p>
<p class="MsoNormal"><b><span style="font-size:16pt">Position 1: </span></b><span style="font-size:16pt">Deep
learning in protein bioinformatics. <span></span></span></p>
<p class="MsoNormal">We apply modern machine learning methods for various protein
structure prediction problems.<span></span></p>
<p class="MsoNormal"><b><span style="font-size:16pt">Position 2: </span></b><span style="font-size:16pt">Ab-Initio
Structure Prediction using PconsC3.<b><span></span></b></span></p>
<p class="MsoNormal">We have recently developed an ab-initio method to predict
the structure of more than 2000 Pfam families. Here we will both improve this
method and use it to gain biological insights in these proteins.<span></span></p>
<p class="MsoNormal"><b><span style="font-size:16pt">Position 3: </span></b><span style="font-size:16pt">Evolution
of transporters and channels.<span></span></span></p>
<p class="MsoNormal">We are studying the evolution of protein transporters and
channels both to understand their function and predict their structures. Here,
we are closely collaborating with experimental colleagues.<span></span></p>
<p class="MsoNormal"><span> </span></p>
<p class="MsoNormal"><span style="font-size:16pt">Selected Publications<span></span></span></p>
<p class="gmail-MsoListParagraphCxSpFirst"><span style="font-size:10pt;font-family:symbol">·<span style="font-variant-numeric:normal;font-stretch:normal;font-size:7pt;line-height:normal;font-family:"times new roman""> </span></span><span style="font-size:10pt;font-family:times">Uziela, K., Menendez Hurtado, D., Shu,
N., Wallner, B. and Elofsson, A. (Epub 2017) ProQ3D: improved model quality
assessments using deep learning. <i>Bioinformatics</i><span></span></span></p>
<p class="gmail-MsoListParagraphCxSpMiddle"><span style="font-size:10pt;font-family:symbol">·<span style="font-variant-numeric:normal;font-stretch:normal;font-size:7pt;line-height:normal;font-family:"times new roman""> </span></span><span style="font-size:10pt;font-family:times">Hayat, S., Peters, C., Shu, N.,
Tsirigos, K.D. and Elofsson, A. (2016) Inclusion of dyad-repeat pattern
improves topology prediction of transmembrane beta-barrel proteins. <i>Bioinformatics</i> <b>32</b> (10)
: 1571-1573.<span></span></span></p>
<p class="gmail-MsoListParagraphCxSpMiddle"><span style="font-size:10pt;font-family:symbol">·<span style="font-variant-numeric:normal;font-stretch:normal;font-size:7pt;line-height:normal;font-family:"times new roman""> </span></span><span style="font-size:10pt;font-family:times;color:black">Shiota, T., Imai, K., Qiu,
J., Hewitt, V.L., Tan, K., Shen, H.H., Sakiyama, N., Fukasawa, Y., Hayat, S.,
Kamiya, M., Elofsson, A., Tomii, K., Horton, P., Wiedemann, N., Pfanner, N.,
Lithgow, T. and Endo, T. (2015) Molecular architecture of the active
mitochondrial protein gate. <i>Science</i> <b>349</b> (6255) :
1544-1548.</span><span style="font-size:10pt;font-family:times"><span></span></span></p>
<p class="gmail-MsoListParagraphCxSpMiddle"><span style="font-size:10pt;font-family:symbol">·<span style="font-variant-numeric:normal;font-stretch:normal;font-size:7pt;line-height:normal;font-family:"times new roman""> </span></span><span style="font-size:10pt;font-family:times">Tsirigos, K.D., Peters, C., Shu, N.,
Kall, L. and Elofsson, A. (2015) The TOPCONS web server for consensus
prediction of membrane protein topology and signal peptides. <i>Nucleic
Acids Res</i> <b>43</b> (W1) : W401-W407.<span></span></span></p>
<p class="gmail-MsoListParagraphCxSpLast"><span style="font-size:10pt;font-family:symbol">·<span style="font-variant-numeric:normal;font-stretch:normal;font-size:7pt;line-height:normal;font-family:"times new roman""> </span></span><span style="font-size:10pt;font-family:times;color:black">Hayat, S., Sander, C.,
Marks, D.S. and Elofsson, A. (2015) All-atom 3D structure prediction of
transmembrane beta-barrel proteins from sequences. <i>Proc Natl Acad Sci U
S A</i> <b>112</b> (17) : 5413-5418.</span><span style="font-size:10pt;font-family:times"><span></span></span></p>
<div><div class="gmail_signature"><div dir="ltr"><div class="gmail_signature"><div dir="ltr"> <br>Yours<br><br>Arne<br><i><br></i>-----------------------------------------<br> Arne Elofsson Science for Life Laboratory<br> Tel:+46-(0)70 695 1045 Stockholm University<br> <a href="http://bioinfo.se/" target="_blank">http://bioinfo.se/</a> Box 1031, <br> Email: <a href="mailto:arne@bioinfo.se" target="_blank">arne@bioinfo.se</a> 17121 Solna, Sweden<br> Twitter: <a href="https://twitter.com/arneelof" target="_blank">https://twitter.com/arneelof</a><br> Scholar: <a href="http://scholar.google.se/citations?user=s3OCM3AAAAAJ" target="_blank">http://scholar.google.se/citations?user=s3OCM3AAAAAJ</a><br> ORCID: 0000-0002-7115-9751</div></div></div></div></div>
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