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Hello everyone,</div>
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There is an open postdoc position in my group in Göteborg, for anyone interested in computational cancer genomics:</div>
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Our main web lab page is down at the moment (sorry) but here’s a bit of information about the group!:</div>
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<div class=""><font face="Roboto, RobotoDraft, Helvetica, Arial, sans-serif" class=""><span style="caret-color: rgba(0, 0, 0, 0.87); color: rgba(0, 0, 0, 0.87); font-size: 14px;" class=""><a href="https://www.gu.se/en/research/erik-larsson" class="">https://www.gu.se/en/research/erik-larsson</a></span></font></div>
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With best wishes,</div>
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Erik Larsson Lekholm</div>
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Select papers:</div>
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<p class="MsoNormal">Elias E, Ardalan A, Lindberg M, Reinsbach SE, Muth A, Nilsson O, Arvidsson Y, <b class="">Larsson E</b>. Independent somatic evolution underlies clustered neuroendocrine tumors in the human small intestine.<br class="">
<b class=""><i class="">Nature Communications.</i></b> 2021 Nov 4. </p>
<p class="MsoNormal">Elliott K, <b class="">Larsson E</b>. Non-coding driver mutations in human cancer.<br class="">
<b class=""><i class="">Nature Reviews Cancer.</i></b> 2021 Jul 6. Review.</p>
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<p class="MsoNormal">Van den Eynden J, Jiménez-Sánchez A, Miller ML, <b class="">Larsson E</b>. Lack of detectable neoantigen depletion signals in the untreated cancer genome.<br class="">
<b class=""><i class="">Nature Genetics.</i></b> 2019 Nov 25.</p>
<p class="MsoNormal">Lindberg M, Boström M, Elliott K, <b class="">Larsson E</b>. Intragenomic variability and extended sequence patterns in the mutational signature of ultraviolet light.<br class="">
<b class=""><i class="">Proc Natl Acad Sci U S A.</i></b> 2019 Sep 23.</p>
<p class="MsoNormal">Persson Ö, Muthukumar Y, Basu S, Jenninger L, Uhler JP, Berglund AK, McFarland R, Taylor RW, Gustafsson CM, <b class="">Larsson E*</b>, Falkenberg M*. Copy-choice recombination during mitochondrial L-strand synthesis causes DNA deletions.<br class="">
<b class=""><i class="">Nature Communications.</i></b> 2019 Feb 15.</p>
<p class="MsoNormal">Elliott K, Boström M, Filges S, Lindberg M, Van den Eynden J, Ståhlberg A, Clausen AR, <b class="">Larsson E</b>. Elevated pyrimidine dimer formation at distinct genomic bases underlies promoter mutation hotspots in UV-exposed cancers.<br class="">
<b class=""><i class="">PLoS Genetics.</i></b> 2018 Dec 26.</p>
<p class="MsoNormal">Fredriksson NJ, Elliott K, Filges S, Van den Eynden J, Ståhlberg A, <b class="">Larsson E</b>. Recurrent promoter mutations in melanoma are defined by an extended context-specific mutational signature.<br class="">
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<p class="MsoNormal">Van den Eynden J, Basu S, <b class="">Larsson E</b>. Somatic Mutation Patterns in Hemizygous Genomic Regions Unveil Purifying Selection during Tumor Evolution.<br class="">
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<p class="MsoNormal">Alaei-Mahabadi B, Bhaduryb J, Karlsson JW, Nilsson JA, <b class="">Larsson E</b>. Global analysis of somatic structural genomic alterations and their impact on gene expression in diverse human cancers.<br class="">
<b class=""><i class="">Proc Natl Acad Sci U S A.</i></b> 2016 Nov.</p>
<p class="MsoNormal">Ashouri A, Sayin VI, Van den Eynden J, Singh SX, Papagiannakopoulos T, <b class="">Larsson E</b>. Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events.<br class="">
<b class=""><i class="">Nature Communications.</i></b> 2016 Oct.</p>
<p class="MsoNormal">FocalScan: Scanning for altered genes in cancer based on coordinated DNA and RNA change. Karlsson J, <b class="">Larsson E</b>.<br class="">
<b class=""><i class="">Nucleic Acids Res.</i></b> 2016 Jul 29.</p>
<p class="MsoNormal">Stewart JB, Alaei-Mahabadi B, Sabarinathan R, Samuelsson T, Gorodkin J, Gustafsson CM, <b class="">Larsson E</b>. Simultaneous DNA and RNA Mapping of Somatic Mitochondrial Mutations across Diverse Human Cancers.<br class="">
<b class=""><i class="">PLoS Genetics</i></b> 2015 Jun 30.</p>
<p class="MsoNormal">Fredriksson NJ, Ny L, Nilsson JA, <b class="">Larsson E</b>. Systematic analysis of noncoding somatic mutations and gene expression alterations across 14 tumor types.<br class="">
<b class=""><i class="">Nature Genetics.</i></b> 2014 Dec.</p>
<p class="MsoNormal">Tang K, Alaei-Mahabadi B, Samuelsson T, Lindh M, <b class="">Larsson E</b>. The landscape of viral expression and host gene fusion and adaptation in human cancer.<br class="">
<b class=""><i class="">Nature Communications.</i></b> 2013 Oct 1.</p>
<p class="MsoNormal">Ashwini J, Marks DS, <b class="">Larsson E</b>. miRcode: a map of putative microRNA target sites in the long non-coding transcriptome.<br class="">
<b class=""><i class="">Bioinformatics.</i></b> 2012 Aug 1.<o:p class=""></o:p></p>
<p class="MsoNormal"><br class="">
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