[Socbin] Joint PhD position at CWI and NKI, Amsterdam

Gunnar W. Klau Gunnar.Klau at cwi.nl
Fri Jan 30 14:35:48 CET 2009


The National Centre for Mathematics and Computer Science (CWI) and the  
Netherlands Cancer Institute (NKI), both located in Amsterdam, The  
Netherlands, invite applications for a jointly advised PhD position on

Subnetwork module construction for improved diagnostic classification  
and subtyping

CWI is the national research institute for mathematics and computer  
science in the Netherlands. CWI performs frontier research in  
mathematics and computer science and transfers new knowledge in these  
fields to society in general and trade and industry in particular. The  
newly established Life Sciences group develops algorithms, theory, and  
models, and performs simulations for a wide range of biological topics  
with a strong focus on systems biology.

The Netherlands Cancer Institute is the only dedicated cancer center  
in the Netherlands and maintains an important role as a national and  
international center of scientific and clinical expertise, development  
and training.  Research within the Netherlands Cancer Institute covers  
all major areas of cancer research, with a strong emphasis on  
translational research. The Bioinformatics and Statistics group  
closely collaborates with basic scientists and clinicians and conducts  
research on a wide range of topics, focusing on integrative  
bioinformatics.

The opening is a research position within the field of bioinformatics/ 
computational biology and will be a joint appointment between the two  
institutes. The research will be carried out in close collaboration of  
the involved partners.

The successful candidate will contribute to building better predictors  
of disease outcome based on functional interaction network modules,  
which are predictive of a specified phenotype, e.g., outcome in  
cancer. To this end, development of new algorithms to detect these  
modules given a complex interaction graph has to be combined with  
protocols for building predictive classifiers given the activation  
patterns of the retrieved modules.

The ideal candidate has a background in bioinformatics, computer  
science, statistics, physics, or biology, strong algorithmic and/or  
machine learning skills, and experience with the analysis of high- 
throughput data.

Applications consisting of motivation letter, Curriculum Vitae, a list  
of publications, and a list of references should be send by email  
before 15 March 2009 to Dr. G.W. Klau or Dr. L.F.A. Wessels, who can  
also supply further information about this position. Please see the  
website http://www.cwi.nl/en/node/961 for further details.


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