[SocBiN] ERC project - Postdoctoral Researcher

Rune Linding rune.linding at gmail.com
Tue Mar 24 14:32:13 CET 2015


Postdoc position in computational modeling of kinase specificity in cancer
and evolution
A postdoc position is available in the laboratory of Prof Dr Rune Linding,
a world-leading network biologist whose research focuses on the mechanisms
by whi­ch cells use signaling networks to respond and adapt to changes in
their environment. We are seeking a highly motivated and brilliant postdoc
to join our highly dynamic, productive and stimulating lab.

*The group and our research*
The Linding Laboratory is a network biology research group based at the
Biotech Research and Innovation Centre at the University of Copenhagen
(BRIC). Our lab explores biological systems by both generating
high-throughput data and developing algorithms aimed at predicting cell
behavior with accuracy similar to those of weather or aircraft models. A
major focus of our lab is studying cellular signal processing and
decision-making during cancer progression.
*Project/The research project(s)*
In this position, the successful applicant will develop computational
models and tools (such as NetworKIN and NetPhorest) to integrate genomic,
quantitative phospho-proteomic and phenotypic data to investigate the drift
in kinase specificity during natural evolution and cancer development.
The generated models will be related to our recent studies on
phosphorylation networks and network medicine (Creixell et al. 2012 Nature
Biotechnology
<http://www.lindinglab.org/Publications/lindinglab-dtu/copy11_of_paper-template>
, Erler & Linding Cell 2012
<http://www.lindinglab.org/Publications/lindinglab-dtu/copy9_of_paper-template>
, Bakal, Linding et al. Science 2008
<http://www.lindinglab.org/Publications/lindinglab-icr-2008-present/copy3_of_paper-template>
, Tan et al. Science 2009
<http://www.lindinglab.org/Publications/lindinglab-icr-2008-present/copy6_of_paper-template>
 and Tan et al. Science 2011
<http://www.lindinglab.org/Publications/lindinglab-dtu/copy18_of_paper-template>
 and Jørgensen et al. Science 2009
<http://www.lindinglab.org/Publications/lindinglab-icr-2008-present/copy12_of_paper-template>).
The ERC funded project is a collaboration between the Linding Laboratory,
Prof. Mike Yaffe’s lab at MIT, and Prof. Ben Turk’s lab at Yale.

*Start: *As soon as possible.
*Duration: *Until 31st October 2016 with the possibility of extension

*Qualifications*
Candidates should hold a PhD degree or equivalent in computational biology,
computer science, physics, bioengineering or other relevant field.
Experience in Bayesian statistical analysis and Machine Learning, high
performance computing, analysis of proteomics, DNA and RNA sequencing,
and/or large-scale systems studies is a distinct advantage. Experience with
signal transduction, bioinformatics and/or programming (Python, R, C++, C
and/or FORTRAN) is also desirable.
The post-holder must be keen to analyze and computationally handle
large-scale quantitative data to reach a deeper understanding of the
biological question at hand. Applicants should be able to work
independently and to plan and carry out complicated tasks, while also being
part of a large and dynamic group. Strong communication skills in English,
both written and spoken are required.

*Place of employment*
The successful applicant would be employed at BRIC, University of
Copenhagen. However the laboratory is physically based on the Technical
University of Denmark’s campus in Lyngby.

Please read more about Linding Laboratory on www.lindinglab.org

For further information regarding the position, please contact Professor
Linding at +45 2365 1941 or linding at lindinglab.org.

*Terms of salary and employment*
Salary, pension and terms of employment will be in accordance with the
agreement between the Ministry of Finance and The Academics Central
organization. Currently, the monthly salary starts at 31.951 DKK/ca. 4.250
Euro plus pension. Depending on qualifications, a higher salary may be
negotiated. The candidate will receive a high monthly retirement supplement
in addition to the salary.

The postdoctoral salary in Denmark is one of the best world-wide. Non-Danish
and Danish applicants may be eligible for a low flat-rate tax (26%+8%),
while remaining fully eligible for all public services of the Danish
well-fare societytax reductions. The applicant must hold a PhD degree and
not have lived in Denmark the last 10 years.

The position is covered by the “Memorandum on Job Structure for Academic
Staff at the Universities” of June 28, 2013.

*Application*
Your application for must be submitted electronically by clicking ‘Apply
now’ belowor via the university’s job portal on
http://employment.ku.dk/faculty/.  The application must include the
following documents/attachments, which must all be in PDF format:


   1. Motivated letter of application (max. one page).
   2. CV incl. education, work/research experience, language skills and
   other skills relevant for the position.
   3. A certified/signed copy of a) PhD certificate and b) Master of
   Science certificate. If the PhD is not completed, a written statement from
   the supervisor will do.
   4. List of publications.

*Letters of recommendation*
Furthermore, the applicant should provide two letters of recommendation. To
be taken into consideration, *the letters must be signed by the supporting
persons on paper with institutional letter head and in PDF-format*. These
should be received before the deadline on jobs at bric.ku.dk with the subject
“name candidate-postdocERC-April2015”; preferably by the supporting
persons. Please make sure that an easy match between the recommendation
letter and the individual applicant is possible.

*Application deadline: 26th April 2015**.*

We reserve the right not to consider applications or supplementary material
received after deadline, and not to consider applications or letters of
recommendation that do not live up to the above-mentioned requirements.

Applications will be assessed according to the Ministry Order on the
Appointment of Academic Staff at Universities 2012 and the University of
Copenhagen’s guidelines 2013. In addition to the required qualifications,
the main criteria for selection will be a strong research potential,
personal drive and experience with the above mentioned techniques, methods
and area of research.

*University of Copenhagen wish to reflect the diversity of society and
welcome applications from all qualified candidates regardless of personal
background.*
APPLY NOW
<http://ssl1.peoplexs.com/Peoplexs22/CandidatesPortalNoLogin/ApplicationForm.cfm?PortalID=12921&VacatureID=725378>

The University of Copenhagen actively influences current and future
generations through excellent research, education and co-operation. UCPH is
one of the highest ranked universities in Europe and is Denmark’s oldest
university, founded in 1479. Today, the University has 40,000 students and
9,000 employees affiliated across six faculties: humanities, law, natural
sciences, social sciences, health sciences and theology.



-- 

Rune Linding, PhD

Professor, Research Group Leader

Biotech Research and Innovation Center (BRIC)

University of Copenhagen (UCPH)

DK-2200 Copenhagen, DENMARK

T +45 2365  1941 / F +45 7262 0285

www.lindinglab.org

www.bric.ku.dk
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