[SocBiN] Postdoc Position in Evolutionary Genomics at the Max Planck Institute

[Michael Hiller]

Computational / Experimental Postdoc Position 

The Research Group “Computational Biology and Evolutionary Genomics” 
at the Max Planck Institute in Dresden, Germany has a Postdoc opening. 


Project description:

The postdoc will utilize numerous sequenced mammalian genomes to 
discover the genomic basis of repeatedly evolved phenotypic differences. 
By focusing on natural phenotypes that resemble human diseases, we aim 
at connecting basic evolutionary with translational research to identify novel 
genes associated with genetic disorders. 

The postdoc will apply and further develop our genomics methods, and 
analyze the results by integrating biomedical knowledge and functional 
genomics data. Promising candidate genes will be tested experimentally, 
either by the Postdoc or in collaboration. The Postdoc will work closely with 
other members of the lab and our institute on the computational and 
experimental aspects. Funding is according to the German TVöD scale.
 

Our group:

We combine computational biology, comparative genomics and experiment 
to investigate how nature's fascinating phenotypic diversity evolved and 
how it is encoded in the genome. On the computational side, we generate 
high-quality genome alignments, apply comparative methods to discover 
key differences in genes and regulatory elements, and use statistical 
approaches to associate genomic to phenotypic differences. On the 
experimental side, we use RNA-seq, ATAC-seq, functional assays and 
CRISPR-Cas9 to reveal the molecular function of genomic regions and 
to test causality between genomic and phenotypic differences.
 
Our group is located at the Max Planck Institute of Molecular Cell Biology 
and Genetics (MPI-CBG) and we are jointly affiliated with the Max Planck 
Institute for the Physics of Complex Systems (MPI-PKS), both in Dresden. 
Both institutes are highly interactive and interdisciplinary workplaces, provide 
an international atmosphere with English as working language and access to 
cutting-edge computational and experimental infrastructure and facilities. The 
MPI-CBG was awarded one of the “Best Places To Work for Postdocs” in 2011.
 

Requirements:

Applicants with a background in both computational and biological sciences 
are encouraged to apply. Applicants with a computational background should 
have a strong interest in integrating experiments in their research and a desire 
to deeply understand the biology underlying mammalian phenotypes and human 
disease. Applicants with a biological background should be experienced in using 
text file processing tools in a Linux shell environment and should have good 
programming skills, for example in a scripting language. Excellent communication 
skills and a strong publication record is expected. Previous experience in 
large-scale genomic data analysis is an advantage.
 

How to apply:

If interested, please email
- your CV including publication list and contact information for at least two references
- a summary of previous research experience (max 1 page) 
to Michael Hiller (hiller at mpi-cbg.de <mailto:hiller at mpi-cbg.de>).
Further information: https://www.mpi-cbg.de/hiller <https://www.mpi-cbg.de/hiller>
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