[SocBiN] Postdoc and Research Assistant in Computational Biology (Uppsala University)

[Marcel Tarbier]

*Postdoc and Research Assistant in Computational Biology (Uppsala
University)*
*with a focus on feature inference from single-cell and spatial
transcriptomics data*

Postdoc: https://uu.varbi.com/en/what:job/jobID:795983/
Research Assistant: https://uu.varbi.com/en/what:job/jobID:805566/
Both data scientists and life scientists are invited to apply!
*Application deadline: 31 March 2025*

We are looking for 1-2 postdoctoral researchers and 1-2 research assistants
(transition into a PhD possible!) in Computational Biology, Bioinformatics
or Data Science. The research group is connected to SciLifeLab and is part
of the National Program for Data-driven Life Science (DDLS).
The lab's research is focused on computational method development
(statistical approaches and machine learning) for single-cell gene
expression data (such as single-cell RNA-sequencing, spatial
transcriptomics and in situ sequencing) to infer complex cell features. The
two main projects aim to infer cellular lineage relationships and cellular
micro-environments respectively. This in turn lays the basis for
applications in precision medicine related to human biopsies and cancer
heterogeneity.
The candidates will have the opportunity to individually drive the projects
forward and develop their own line of research as well as to extent their
skills at the intersection of mathematics, programming and biology.
https://www.scilifelab.se/researchers/marcel-tarbier/

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*Requirements*
PhD degree (for postdoc) or Master's degree (for research assistant) in
computational biology, bioinformatics, biostatistics, data science, applied
statistics, machine learning, biotechnology, molecular biology/medicine or
equivalent or a foreign degree equivalent to a PhD degree / Master's
degree. The degree needs to be obtained by the time of the decision of
employment.

Skills at the intersection of mathematics, programming and biology are
required. The applicant should have experience in two of these fields and
an interest in learning about the remaining one.
The candidate is required to possess a strong command of R or python
programming as well as experience in the development of original code for
data analysis. Experience in statistics, handling of big datasets, data
analysis and visualization is expected. Fluency in written and spoken
English is necessary.

*Additional qualifications*

Any of the following skills is considered a merit.
· Experience with single-cell RNA-sequencing, spatial transcriptomics or in
situ sequencing
· Experience in handling technical and other biases in the data and in
handling complex data with interdependent features
· Experience with HPC, parallelization and handling of large datasets
· Experience in feature inference (e.g., inferring an unobserved external
factor through its footprint in the data, i.e., transcription factor
activity from RNA-sequencing data)
· Experience in multi-omics integration, machine learning or RNA
pseudo-time and velocity analyses

*About the employment*

Postdoc: The employment is a temporary position of 2 years according to
central collective agreement, with possibility of 1 year extension. Full
time position. Starting date as agreed.

Research Assistant: The employment is a temporary position, 6 months with
possibility of extension.  Full time position. Starting date as agreed.

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*Marcel Tarbier*
DDLS-Fellow / Assistant Professor in Data-Driven Life Sciences
for Precision Medicine and Diagnostics
SciLifeLab and Uppsala University
scilifelab.se/researchers/marcel-tarbier

Department of Immunology, Genetics and Pathology
Rudbeck laboratory
751 85 UPPSALA
Sweden
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