[SocBiN] Industry PhD position in Computational Protein Design

[Arne Elofsson]

Come work with me an Sarah and become a part of DDLS



https://danaher.wd1.myworkdayjobs.com/CytivaJobsPP/job/Stockholm-Sweden/Industry-PhD-position-in-Computational-Protein-Design_R1288993



Industry PhD position in Computational Protein Design
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<https://danaher.wd1.myworkdayjobs.com/CytivaJobsPP/job/Stockholm-Sweden/Industry-PhD-position-in-Computational-Protein-Design_R1288993/apply>
locationsStockholm, Sweden
time typeFull time
posted onPosted Yesterday
job requisition idR1288993

We are looking for a motivated PhD student to join us in a unique,
collaborative project between our Affinity Ligand Design team at Cytiva and
the Elofsson group at Stockholm University, where we will use machine
learning methods to develop affinity ligands. These methods have been
transformative for protein design, allowing generation of novel proteins
which can suit a precise need. In this 4 year project, funded by the DDLS
program, we aim to develop AI-based tools in design of affinity ligands,
such as the prediction of binding interactions between proteins.

Data-driven life science (DDLS) uses data, computational methods and
artificial intelligence to study biological systems and processes at all
levels, from molecular structures and cellular processes to human health
and global ecosystems. The SciLifeLab and Wallenberg National Program for
Data-Driven Life Science (DDLS) aims to recruit and train the next
generation of data-driven life scientists and to create globally leading
computational and data science capabilities in Sweden. The program is
funded with a total of 3.3 billion SEK over 12 years from the Knut and
Alice Wallenberg (KAW) Foundation.

In 2025, the DDLS Research School will be expanded with the recruitment of
19 academic and 7 industrial PhD students. During the course of the DDLS
program more than 260 PhD students and 200 postdocs will be part of the
Research School. The DDLS program has four strategic research areas: cell
and molecular biology, evolution and biodiversity, precision medicine and
diagnostics, epidemiology and biology of infection. For more information,
please see https://www.scilifelab.se/data-driven/ddls-research-school/ The
future of life science is data-driven. Will you be part of that change?
Then join us in this unique program!

The Elofsson group is located at the Science for Life Laboratory. Elofsson
has worked on protein structure predictions for more than two decades and
on various techniques using machine learning and other computational
techniques. Some of his most important contributions to this work are the
methods he has developed to improve the prediction of membrane protein,
protein structures and protein interactions. The group comprises four PhD
students, one postdoc, and one senior researcher. For recent publications,
see here: https://archive.bioinfo.se/papers/

Cytiva’s Affinity Ligand Design team is a small unit of our company,
located in the Karolinska campus, and is responsible for discovering and
designing new affinity purification ligands and solutions for the next
generation of biopharmaceuticals. We consist of about 15 experts in the
field of protein engineering, protein production, affinity ligand design
and characterization, and machine learning for protein design.

This unique PhD position is a 4-year collaborative project where you will
work at the Cytiva Solna and Elofsson lab environments, both located at the
Solna Campus. Upon successfully completing the 4-year project, you will
obtain a PhD in Bioinformatics from Stockholm University.

*Requirements:*

   - An MSc, including a thesis of at least 30 hp in Biotechnology,
   Bioinformatics, or related fields.
   - English as a working language, with Swedish as a strong merit.
   - Experience in Python programming.
   - Experience with machine learning methods, bioinformatics, and data
   science.
   - Familiarity with generative AI tools for protein design and protein
   language models.
   - Knowledge of protein structure, function, and interactions.
   - It is a merit if you have knowledge of protein engineering,
   characterization and/or purification methods.
   - A valid EU work permit is required.

Please submit your application no later than June 29th. For questions
regarding the role, please contact Professor Arne Elofsson at
arne at bioinfo.se or the Project Manager at Cytiva, Sarah McComas at
sarah.mccomas at cytiva.com.

Join our winning team today. Together, we’ll accelerate the real-life
impact of tomorrow’s science and technology. We partner with customers
across the globe to help them solve their most complex challenges,
architecting solutions that bring the power of science to life.

For more information, visit www.danaher.com.

At Danaher, we value diversity and the existence of similarities and
differences, both visible and not, found in our workforce, workplace and
throughout the markets we serve. Our associates, customers and shareholders
contribute unique and different perspectives as a result of these diverse
attributes.




Yours

Arne

-----------------------------------------
  Arne Elofsson                  Science for Life Laboratory
  Tel:+46-(0)70 695 1045   Stockholm University
  http://bioinfo.se/               Box 1031,
  Email: arne at bioinfo.se   17121 Solna, Sweden
Bluesky: @bioinfo.se
Twitter/X: @arneelof
  Mastodon: @arneelof at fediscience.org
  Zoom: https://stockholmuniversity.zoom.us/my/arneelof/
  Scholar: http://scholar.google.se/citations?user=s3OCM3AAAAAJ
  ORCID: 0000-0002-7115-9751 <https://orcid.org/0000-0002-7115-9751>
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