[SocBiN] Postdoc in computational cancer genomics in Gothenburg

Erik Lekholm erik.larsson at gu.se
Tue Oct 4 10:32:07 CEST 2022


Hello everyone,

There is an open postdoc position in my group in Göteborg, for anyone interested in computational cancer genomics:

https://web103.reachmee.com/ext/I005/1035/job?site=7&lang=UK&validator=9b89bead79bb7258ad55c8d75228e5b7&job_id=27307

Our main web lab page is down at the moment (sorry) but here’s a bit of information about the group!:

https://www.gu.se/en/research/erik-larsson

With best wishes,

Erik Larsson Lekholm


Select papers:

Elias E, Ardalan A, Lindberg M, Reinsbach SE, Muth A, Nilsson O, Arvidsson Y, Larsson E. Independent somatic evolution underlies clustered neuroendocrine tumors in the human small intestine.
Nature Communications. 2021 Nov 4.
Elliott K, Larsson E. Non-coding driver mutations in human cancer.
Nature Reviews Cancer. 2021 Jul 6. Review.
Basu S, Xie X, Uhler JP, Hedberg-Oldfors C, Milenkovic D, Baris OR, Kimoloi S, Matic S, Stewart JB, Larsson NG, Wiesner RJ, Oldfors A, Gustafsson CM, Falkenberg M, Larsson E. Accurate mapping of mitochondrial DNA deletions and duplications using deep sequencing.
PLoS Genetics. 2020 Dec 14.
Van den Eynden J, Jiménez-Sánchez A, Miller ML, Larsson E. Lack of detectable neoantigen depletion signals in the untreated cancer genome.
Nature Genetics. 2019 Nov 25.
Lindberg M, Boström M, Elliott K, Larsson E. Intragenomic variability and extended sequence patterns in the mutational signature of ultraviolet light.
Proc Natl Acad Sci U S A. 2019 Sep 23.
Persson Ö, Muthukumar Y, Basu S, Jenninger L, Uhler JP, Berglund AK, McFarland R, Taylor RW, Gustafsson CM, Larsson E*, Falkenberg M*. Copy-choice recombination during mitochondrial L-strand synthesis causes DNA deletions.
Nature Communications. 2019 Feb 15.
Elliott K, Boström M, Filges S, Lindberg M, Van den Eynden J, Ståhlberg A, Clausen AR, Larsson E. Elevated pyrimidine dimer formation at distinct genomic bases underlies promoter mutation hotspots in UV-exposed cancers.
PLoS Genetics. 2018 Dec 26.
Fredriksson NJ, Elliott K, Filges S, Van den Eynden J, Ståhlberg A, Larsson E. Recurrent promoter mutations in melanoma are defined by an extended context-specific mutational signature.
PLoS Genetics. 2017 May 10.
Van den Eynden J, Basu S, Larsson E. Somatic Mutation Patterns in Hemizygous Genomic Regions Unveil Purifying Selection during Tumor Evolution.
PLoS Genetics. 2016 Dec 27.
Alaei-Mahabadi B, Bhaduryb J, Karlsson JW, Nilsson JA, Larsson E. Global analysis of somatic structural genomic alterations and their impact on gene expression in diverse human cancers.
Proc Natl Acad Sci U S A. 2016 Nov.
Ashouri A, Sayin VI, Van den Eynden J, Singh SX, Papagiannakopoulos T, Larsson E. Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events.
Nature Communications. 2016 Oct.
FocalScan: Scanning for altered genes in cancer based on coordinated DNA and RNA change. Karlsson J, Larsson E.
Nucleic Acids Res. 2016 Jul 29.
Stewart JB, Alaei-Mahabadi B, Sabarinathan R, Samuelsson T, Gorodkin J, Gustafsson CM, Larsson E. Simultaneous DNA and RNA Mapping of Somatic Mitochondrial Mutations across Diverse Human Cancers.
PLoS Genetics 2015 Jun 30.
Fredriksson NJ, Ny L, Nilsson JA, Larsson E. Systematic analysis of noncoding somatic mutations and gene expression alterations across 14 tumor types.
Nature Genetics. 2014 Dec.
Tang K, Alaei-Mahabadi B, Samuelsson T, Lindh M, Larsson E. The landscape of viral expression and host gene fusion and adaptation in human cancer.
Nature Communications. 2013 Oct 1.
Ashwini J, Marks DS, Larsson E. miRcode: a map of putative microRNA target sites in the long non-coding transcriptome.
Bioinformatics. 2012 Aug 1.

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