[Socbin] Fwd: industry sponsored DPhil studentship - University of Oxford

Tue Jun 12 19:19:03 CEST 2007

---------- Forwarded message ----------
From: Anna Mathews <mathews at stats.ox.ac.uk>
Date: Tue, 12 Jun 2007 16:04:27 +0100
Subject: industry sponsored DPhil studentship - University of Oxford
To: "jvanheld at scmbb.ulb.ac.be" <'jvanheld at scmbb.ulb.ac.be'>,
"bran at ulb.ac.be" <'bran at ulb.ac.be'>, "yves.moreau at esat.kuleuven.ac.be"
<'yves.moreau at esat.kuleuven.ac.be'>, "pierre.rouze at psb.ugent.be"
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<'kristian at icgeb.org'>, "annec at cbs.dtu.dk" <'annec at cbs.dtu.dk'>,
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<'anne.chesneau at biotec.tu-dresden.de'>, "Ray.Walshe at computing.dcu.ie"
<'Ray.Walshe at computing.dcu.ie'>, "anna.tramontano at uniroma1.it"
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<'dsatijn at science.uva.nl'>, "Eivind.Coward at ii.uib.no"
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"A.J.Baines at kent.ac.uk" <'A.J.Baines at kent.ac.uk'>, "pmiller at liv.ac.uk"
<'pmiller at liv.ac.uk'>, "scipg at uea.ac.uk" <'scipg at uea.ac.uk'>,
"sandm at shu.ac.uk" <'sandm at shu.ac.uk'>, "cav-admissions at wmin.ac.uk"
<'cav-admissions at wmin.ac.uk'>, "ThomasJM2 at cardiff.ac.uk"
<'ThomasJM2 at cardiff.ac.uk'>, "kenneth.langlands at buckingham.ac.uk"
<'kenneth.langlands at buckingham.ac.uk'>, "Hugh.Shanahan at rhul.ac.uk"
<'Hugh.Shanahan at rhul.ac.uk'>, "cse at dmu.ac.uk" <'cse at dmu.ac.uk'>,
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m.sternberg at imperial.ac.uk
Cc: "Charlotte M. Deane" <deane at stats.ox.ac.uk>

Dear All,

Please could you pass this on to any students who may be interested?

Regards,

Anna Mathews

Bioinformatics Portfolio Manager, University of Oxford

Structural Modelling of Transmembrane Domains

Industry sponsored DPhil studentship in conjunction with UCB Celltech
<http://www.ucb-group.com/>

Applications are invited from highly qualified graduates for a new
industry sponsored DPhil studentship. This position is available from
October 2007. The studentship is open to UK/EU nationals only due to
the nature of the funding and will attract an annual enhanced stipend
of £15,600 in addition to tuition fees. The project would involve a
placement with UCB Celltech.

Project details

Integral membrane proteins constitute about 30% of all known proteins
and play key functional roles in cells. Their function is essential
for a wide range of physiological events, such as neurotransmitter
transport, cell recognition and nerve impulse transmission. Membrane
proteins are therefore important potential drug targets.
Despite their importance, experimentally determined structures are
rare as they are both difficult and expensive to attain. The value of
modelling the structures of these proteins is therefore large.
However, there are no fully automated tools developed specifically for
the structure prediction of membrane proteins as opposed to their
globular soluble counterparts.
The existing state of the art in membrane protein structure prediction
is based on the use of tools developed and trained on globular
proteins and then relies on manual manipulation and specialist
expertise to generate models.
In this project we would utilize the specific structural features that
membrane proteins exhibit to develop a toolkit directed at modelling
them more accurately in a fully automated fashion.

The successful applicant can expect to master skills in a variety of
techniques in bioinformatics. They will also gain knowledge of
membrane protein structure and biology.  Applicants with expertise in
the areas of mathematics, statistics, computer science, biochemistry
or biological sciences would be suitable for this project. Experience
of computer programming would be an advantage.

Given that this project involves collaboration between the
internationally recognised Department of Statistics and UBC Celltech
the studentship provides an ideal opportunity for further career
development within the academic or industrial sector.

For more information please contact Charlotte Deane email: deane at stats.ox.ac.uk

http://www.stats.ox.ac.uk/~deane

Regards,
Anna
Anna Mathews
Bioinformatics Portfolio Manager
Oxford Bioinformatics Programme
University of Oxford
Peter Medawar Building
South Parks Road
Oxford OX1 3SY
Telephone: 01865 281 892
Fax: 01865 281 278
Web: http://bioinfomsc.stats.ox.ac.uk <http://bioinfomsc.stats.ox.ac.uk>

-- 
---------------------------------------------------------
Prof.  Arne Elofsson      Dep of Biochemistry and Biophysics
 Tel:+46-8-16 4672      Stockholm University
 Fax:+46-8-15 3679      10691 Stockholm, Sweden
 Net: arne at bioinfo.se   http://bioinfo.se/