[Socbin] Postdoc in bioinformatics/pathogen paleogenomics

[Anders Krogh]

/*Postdoctoral Fellowship in ancient Phytophthora infestans genomics*/

A two-year postdoctoral fellowship (with possibility of extension) is 
available at the Centre for GeoGenetics, Natural History Museums of 
Denmark, Faculty of Science, University of Copenhagen. Funded by 
Lundbeckfonden (The Lundbeck Foundation), the position will be available 
to commence following January 1st, 2011.
 
*Project area:*
The oomycete /Phytophthora infestans /is one of the most destructive 
commercial crop pathogens. As the causative agent of potato late blight, 
the most important disease of the world´s fourth largest food crop, 
conservative estimates suggest it carries an annual economic cost of 6.7 
billion USD. First observed in the US in 1843, it rapidly spread to 
Europe, and within 2 years had gained notoriety for causing the Irish 
potato famine of 1845, which played a significant effect on western 
history, due to the mass famine and population displacement caused - an 
estimated 1.5 million Irish died from starvation, and a further 1.5 
million were forced to emigrate. Phytophthora infestans exhibits a 
remarkable speed of adaptation to control strategies such as genetically 
resistant cultivars, and the recent appearance of strains resistant to 
the phenylamide fungicide metalaxyl, and the continual arisal of 
increasingly virulent genotypes has lead it to reach epidemic 
proportions globally.
 
Placed jointly within the Bioinformatics group headed by Professor 
Anders Krogh (Institute of Biology), and the Pathogen Paleogenomics 
group headed by Assoc. Professor Tom Gilbert (Natural History Museum), 
the role of the successful applicant will be twofold. Firstly, the 
applicant will be expected to develop computational tools with which to 
assemble and analyze ancient genomic sequences. Secondly, the applicant 
will be expected to apply these (and other tools) to genome level 
sequence analysis of historic /Phytophtora infestans/ samples in order 
to reconstruct 150 years of its genomic evolution.
 
*Qualifications:*
For consideration, applicants must have the following key skills:
a)     PhD in bioinformatics or a related field
b)     Demonstrated experience in the analysis of Next Generation DNA 
Sequencing data (in particular Illumina platform) or genome assembly
c)      Ability to program in PERL or Python, or similar
d)     Having published in high-quality international peer-reviewed journals
*Skills of additional, although not requisite, interest include:*
a)     Understanding of molecular biology, evolutionary biology, ancient DNA
b)     Ability to work with LINUX and program in other languages (e.g. 
C, C++)
c)      International/Genome sequencing centre experience
d)     Experience with target-capture sequence data
 
As the members and collaborators of the Centre are international, the 
working language of the Centre is English, thus excellent English 
speaking, reading and writing skills are required.

*Application:*
The application must contain:
/Curriculum vitae/ (incl. the applicant´s email address)
List of publications
Motivation for applying (0.5 A4-page)
Transcript of university examinations (in English)
Contact details of 2 persons for references
 
For further information please contact Associate Professor Tom Gilbert 
(tgilbert at snm.ku.dk <mailto:tgilbert at snm.ku.dk>)
 
Applications should be e-mailed as one pdf-file marked "Postdoctoral 
Fellowship" to Tom Gilbert (tgilbert at snm.ku.dk 
<mailto:tgilbert at snm.ku.dk>).  

*Deadline for applications is 1st November 2010 at 12:00 noon. 
Applications received after the deadline may not be considered.*

-- 
Anders Krogh                       krogh at binf.ku.dk
Professor                            www.binf.ku.dk
The Bioinformatics Centre
Dept of Biology                  Ph.  +45 3532 1329
University of Copenhagen
Ole Maaloes Vej 5                Dept +45 3532 3710
2200 Copenhagen, Denmark         Fax  +45 3532 1281

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