[SocBiN] A master's thesis/internship project on NGS data handling, Helsinki

[sofiak at kapsi.fi]

Dear all,

We are offering a master's thesis/internship project for one student in
our lab located in Helsinki, Finland.

The research group on hereditary breast cancer susceptibility is
investigating the genetic background of breast cancer as well as breast
and ovarian cancer by identifying genes and genetic variation for cancer
development and progression. We have used exome sequencing to identify
breast or ovarian cancer predisposing variants. Please see Kiiski JI et
al. Exome sequencing identifies FANCM as a susceptibility gene for
triple-negative breast cancer. Proc Natl Acad Sci U S A. 2014. Further
information about the group: http://www.kll.helsinki.fi/groups/nevanlinna/

The aim of this project is to combine different whole exome sequencing
batches (sequenced at different times) and one whole genome sequencing
data set (extracting the exomes) to produce one combined data set that all
the subsequent analyses will be based on. This would require performing
the whole work-flow from raw data to variant calling and variant
annotation. The successful candidate is a motivated student at more
advanced stage of his/her studies in the field of bioinformatics or
related field. The project also enables integrating Master's Thesis as a
part of the work. Some knowledge of the basics of molecular biology would
be desirable. Knowledge of bioinformatics tools for analysis of
next-generation sequencing data would be a major plus. The position is
initially for 3 to 4 months during the summer 2016. The starting date is
negotiable.

For further information about the project, please contact Sofia Khan
(sofia.khan(at)helsinki.fi). Please send applications including cover
letter, CV, and two references to sofia.khan(at)helsinki.fi by 17.4.2016.


Best wishes,
Sofia Khan
Dept. of Obstetrics and Gynecology
Helsinki University Central Hospital
Biomedicum Helsinki
P.O. BOX 700
00029 HUS
Finland