[SocBiN] Fwd: Two bioinformatician positions available

Mon Feb 10 10:17:24 CET 2020

*From: *mbb-gcb-molneuro <MBB-GCB-MOLNEURO at EMAILLIST.KI.SE> on behalf of
Goncalo Castelo-Branco <goncalo.castelo-branco at KI.SE>
*Reply to: *Goncalo Castelo-Branco <goncalo.castelo-branco at ki.se>
*Date: *Monday, 27 January 2020 at 17:20
*To: *"MBB-GCB-MOLNEURO at EMAILLIST.KI.SE" <MBB-GCB-MOLNEURO at EMAILLIST.KI.SE>
*Subject: *two bioinformatician positions

Hi group,

Would you mind spreading the word in your networks?

Thanks!

Best,

Gonçalo

*https://ki.varbi.com/en/what:job/jobID:313855/*
<https://eur01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fki.varbi.com%2Fen%2Fwhat%3Ajob%2FjobID%3A313855%2F&data=02%7C01%7Cmukund.kabbe%40ki.se%7C08aca3e5fde74e9c6eef08d7a344db98%7Cbff7eef1cf4b4f32be3da1dda043c05d%7C0%7C0%7C637157388442651839&sdata=SzhMi3MMbSyTsoOc%2Ff3G%2FBp1N6emICv6c%2BjlzzXNr3U%3D&reserved=0>

Applications for two bioinformatician positions are welcome at the unit of
Molecular Neurobiology (MBB), at Karolinska Institutet, Stockholm, Sweden.
One position will be as a core bioinformatician at the Gonçalo
Castelo-Branco research group
<https://eur01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fki.se%2Fen%2Fmbb%2Fgoncalo-castelo-branco-group&data=02%7C01%7Cmukund.kabbe%40ki.se%7C08aca3e5fde74e9c6eef08d7a344db98%7Cbff7eef1cf4b4f32be3da1dda043c05d%7C0%7C0%7C637157388442661846&sdata=33Wz5IruwiBvaoEbdS9jPKG5P1bA8g%2FXvOtZPUAXNa8%3D&reserved=0>
and
the other position will be for a post-doctoral project, joint with Ana
Mendanha Falcao’s group (also at University of Minho
<https://eur01.safelinks.protection.outlook.com/?url=http%3A%2F%2Fwww.icvs.uminho.pt%2Fabout-icvs%2Fpeople%2Fanaluisafalcao&data=02%7C01%7Cmukund.kabbe%40ki.se%7C08aca3e5fde74e9c6eef08d7a344db98%7Cbff7eef1cf4b4f32be3da1dda043c05d%7C0%7C0%7C637157388442661846&sdata=1AX0skMV5XX2AWfy%2ByCKBN0YPzN631Sd3H1mc382Y5g%3D&reserved=0>,
Portugal).
Your mission

The successful candidates will be actively working in specific projects
with single-cell and bulk transcriptomics and epigenomics, and will be
integrated in a multidisciplinary team comprising computational, molecular
and cellular biologists. The core bioinformatician will also work on web
development, data curation, handling of data integration and visualization
frameworks, among other tasks.
Your profile

We are looking for highly motivated, driven, inquisitive, enthusiastic
persons interested in our area of research, and ready to explore new
avenues in science. The candidates should have a collaborative approach to
research, working productively in a team and contributing to a good social
environment in the laboratory.

The applicants must have at least a Master in bioinformatics and
computational biology (for the core bioinformatician position) or PhD
degree (for the post-doctoral bioinformatician position), and strong
programming skills (R and/or Python and/or others), UNIX and LINUX systems
knowledge, familiarity with data science a big data. Research experience and
expertise in analysis of sequencing data is highly desirable. Wet lab
experience is not required but it is an advantage for the postdoctoral
bioinformatician position.

Note: qualification to be employed for the postdoctoral position is a
doctoral degree or equivalent scientific competence. Applicants who have
not completed a doctorate at the end of the application period may also
apply, provided that all requirements for a completed degree are met before
the (intended) date of employment. This must be substantiated by the
applicant's main supervisor, director or equivalent.
What do we offer?

A creative and inspiring environment full of expertise and curiosity.
Karolinska Institutet is one of the world's leading medical universities.
Our vision is to pursue the development of knowledge about life and to
promote a better health for all. At Karolinska Institutet, we conduct
successful medical research and hold the largest range of medical education
in Sweden. Karolinska Institutet is a state university, which entitles to
several benefits such as extended holiday and generous occupational
pension. Employees also have access to our modern gym for free and receive
reimbursements for medical care.

The Unit of Molecular Neurobiology
<https://eur01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fki.se%2Fen%2Fmbb%2Fresearch-division-of-molecular-neurobiology&data=02%7C01%7Cmukund.kabbe%40ki.se%7C08aca3e5fde74e9c6eef08d7a344db98%7Cbff7eef1cf4b4f32be3da1dda043c05d%7C0%7C0%7C637157388442671828&sdata=L1bb9lBLHvxymVYC0ncQ4BOXSauUDWyvd3YUj4Ap3aU%3D&reserved=0>
has
presently seven research groups, focused on several aspects of development,
stem cell biology, neuroscience and cancer, providing a unique critical
mass and expertize, and vibrant scientific environment.

The Castelo-Branco research group
<https://eur01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fki.se%2Fen%2Fmbb%2Fgoncalo-castelo-branco-group&data=02%7C01%7Cmukund.kabbe%40ki.se%7C08aca3e5fde74e9c6eef08d7a344db98%7Cbff7eef1cf4b4f32be3da1dda043c05d%7C0%7C0%7C637157388442671828&sdata=2HCUXQ5ALW8A6SkrAthafDMPjTrAhYhc%2B7FbYnAw6Ic%3D&reserved=0>
is
interested in the molecular mechanisms defining the epigenetic state of
cells of the oligodendrocyte lineage. We are focused on how interplay
between transcription factors, non-coding RNAs and chromatin modifying
enzymes contribute to the transition between states within the
oligodendrocyte lineage, with the aim to design epigenetic based-therapies
to induce regeneration (remyelination) in demyelinating diseases, such as
multiple sclerosis. Our research group has performed single nuclei/cell
RNA-Seq and identified several cell states within the oligodendrocyte
lineage in development and disease (Science 2016, Dev Cell 2018, Nature
Medicine 2018, Nature 2019). Our findings suggest that oligodendrocyte
lineage cells might present other functional properties than previously
thought.

Dr. Ana Mendanha Falcão has recently established her research group, which
is focusing on the role of the choroid plexus in diseases such as multiple
sclerosis. Her team aims to investigate the choroid plexus as a source of
biologically active molecules to the central nervous system, in order to
influence disease dynamics. The choroid plexus will be studied as an
alternative target for disease therapies since it can be modulated by
peripheral blood and it can substantially alter the brain composition both
in terms of biologically active molecules and immune cell content.

*Location: *Biomedicum, Solna (Stockholm, Sweden)

https://ki.se/en/mbb/goncalo-castelo-branco-group
<https://eur01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fki.se%2Fen%2Fmbb%2Fgoncalo-castelo-branco-group&data=02%7C01%7Cmukund.kabbe%40ki.se%7C08aca3e5fde74e9c6eef08d7a344db98%7Cbff7eef1cf4b4f32be3da1dda043c05d%7C0%7C0%7C637157388442681829&sdata=pl2VorRLoWFDz0Yoc3jYMDEqg1G9xzP6JaDyQrCeHaM%3D&reserved=0>

http://www.icvs.uminho.pt/about-icvs/people/analuisafalcao
<https://eur01.safelinks.protection.outlook.com/?url=http%3A%2F%2Fwww.icvs.uminho.pt%2Fabout-icvs%2Fpeople%2Fanaluisafalcao&data=02%7C01%7Cmukund.kabbe%40ki.se%7C08aca3e5fde74e9c6eef08d7a344db98%7Cbff7eef1cf4b4f32be3da1dda043c05d%7C0%7C0%7C637157388442681829&sdata=MREkExCi1d63L%2BmWj7OGXxr%2BmDIkDA9Gt6I7I6JNfA0%3D&reserved=0>

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